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产品目录

ERAB/HSD17B10抗体图片
产品货号:
Z31054
中文名称:
ERAB/HSD17B10抗体
英文名称:
Anti-ERAB/HSD17B10 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-ERAB/HSD17B10 Antibody
指标别名17 beta HSD 10;17b HSD10;ABAD;CAMR;DUPXp11.22;ERAB;HADH2;HCD2;HSD17B10;MHBD;MRPP2;MRX17;MRX31;MRXS10;SCHAD;SDR5C1;Type II HADH;XH98G2
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC/IF,FCM
基因名称HSD17B10
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human ERAB Functions in mitochondrial tRNA maturation.Part of mitochondrial ribonuclease P,an enzyme composed of MRPP1/RG9MTD1,MRPP2/HSD17B10 and MRPP3/KIAA0391,which cleaves tRNA molecules in their 5'-ends.By interacting with intracellular amyloid-beta,it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
实际分子量25KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料ERAB is also known as HSD17B10 or HADH2.This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II,a member of the short-chain dehydrogenase/reductase superfamily.The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids,and is a subunit of mitochondrial ribonuclease P,which is involved in tRNA maturation.The protein has been implicated in the development of Alzheimer disease,and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency.Several alternatively spliced transcript variants have been identified,but the full-length nature of only two transcript variants has been determined.
Uniprot IDQ99714
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:20~100
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100
Flow cytometry (FCM) 1:20

相关搜索:ERAB/HSD17B10抗体ERAB抗体HSD17B10单抗Anti-ERAB/HSD17B10 Antibody
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